生物医用微纳材料开发：基于磁热等过程强化，研制微纳气泡、磁性微纳材料等生物医用微纳材料。

超临界流体制备微纳材料技术：利用超临界二氧化碳技术制备微纳材料，目前的主要工作包括两亲嵌段聚合物在超临界流体中的自组装；超临界技术制备用于食品和医药的脂质体等。

绿色化工过程开发：利用过程模拟和流场模拟等技术，开发环境友好、节能减排的化工过程新技术等。

附加值精细化学品研制：针对企业技术需求，开发高附加值精细化学品生产工艺，协助企业完成工业化生产。

在研代表性项目：

1.国家自然科学基金重点项目，面向间歇缺氧致脑损伤诊治一体化的纳米磁基元脂质序构体材料，2022.1-2025.12

2.江苏省重点研发计划产业前瞻与核心技术项目，基于微纳气泡强化的集成电路14nm先进制程单片清洗设备研发，2023.9-2026.9

3.苏州市前沿技术研究项目，用于MPI成像的高性能铁基磁性纳米微球材料研发，2023.11-2026.12

4.曹传欣校友发展研究基金，基于微气泡的气-液-固反应体系强化及其用于醇胺氧化耦合反应制备亚胺的研究，2023.7-2025.6

5.苏州市产业前瞻与关键核心技术项目，面向药物递送的功能纳米磁基元脂质序构微球材料研发，2022.11-2025.10

6.苏州市产业前瞻与关键核心技术项目，面向集成电路28nm先进制程的单片清洗设备关键技术研发，2022.11-2025.10

教育经历

1998-2002：南京大学化学化学学院，应用化学，本科

2002-2007：南京大学化学化工学院，物理化学，博士（硕博连续）

工作经历

2007.6-至今：东南大学化学化工学院，讲师，副教授

2015.1-至今：东南大学-蒙纳士大学苏州联合研究院，院长助理；

东南大学-蒙纳士大学纳米生物技术联合研究中心，研究人员

2017.9-2018.9：澳大利亚蒙纳士大学，访问学者

2013.3-2014.12：科学技术部基础研究管理中心，973计划和国家重大科学研究计划联络员

主持或参加了国家自然科学基金、国家高技术研究计划（863计划）、国家科技支撑计划子课题、江苏省自然科学基金、江苏省高技术项目、中石油基础研究项目、江苏省成果转化基金项目、东南大学教师科研启动基金及多项企业横向开发项目。

近年来发表的代表性论文：

[1] Wang X, Wang C, Zha X, Mei Y, Xia J, Jiao Z*, Supercritical carbon dioxide extraction of β-carotene and α-tocopherol from pumpkin :A Box-Behnken design for extraction variables, Analytical Methods, 2017, 9(2): 294-303

DOI: 10.1039/C6AY02862D

[2]  Jiao Z*, Wang X, Yang Q, Wang C, Modification and characterization of urethane acrylate oligomers used for UV-curable coatings, Polymer Bulletin, 2017， 74(7), 2497-2511

DOI: 10.1007/s00289-016-1847-4

[3]  Jiao Z*, Yang Q, Wang X, Wang C, UV-curable hyperbranched urethane acrylate oligomers modified with different fatty acids, Polymer Bulletin, 2017，74(12), 5049-5063

DOI: 10.1007/s00289-017-2003-5

[4] Han S, Wang W, Jiao Z*; Wei X, Solubility of Vitamin E acetate in supercritical carbon dioxide: Measurement and Correlation. Journal of Chemical & Engineering Data, 2017, 62(11), 3854–3860

DOI: 10.1021/acs.jced.7b00550

[5] Jiao Z*, Fan W, Wang X, Wang Z, Synthesis of CO2-philic amphiphilic block copolymers by RAFT polymerization and its application on forming drug-loaded micelles using ScCO2 evaporation method, Journal of Drug Delivery Science and Technology, 2018,44:13-18

DOI: 10.1016/j.jddst.2017.11.024

[6]  Jiao Z*, Wang C, Yang Q, Wang X, Preparation and characterization of UV-curable urethane acrylate oligomers modified with cycloaliphatic epoxide resin，Journal of Coatings Technology and Research, 2018, 15(2): 251-258

DOI: 10.1007/s11998-017-9994-6

[7] Jiao Z*, Wang Z., Wang X., Fan W., Effects of Processing Parameters on the Properties of Amphiphilic Block Copolymer Micelles Prepared by Supercritical Carbon Dioxide Evaporation Method, Polish Journal of Chemical Technology, 2018， 20(1): 81-86.

DIO: 10.2478/pjct-2018-0012

[8] Jiao Z*, Wang X, Yin Y, Wang Z, Mei Y, Xia J, Preparation and evaluation of a chitosan-coated antioxidant liposome containing vitamin C and folic acid, Journal of Microencapsulation, 2018, 35(3): 272-280.

DOI: 10.1080/02652048.2018.1467509

[9] Cheng J, Han S, Song Junying, Wang W, Jiao Z*, Solubility of Vitamin E Acetate in Supercritical Carbon Dioxide with Ethanol as Cosolvent, Journal of Chemical & Engineering Data, 2018, 63(11): 4248–4255

DOI: 10.1021/acs.jced.8b00745

[10] Zha X, Han S, Wang W, Jiao Z*, Experimental measurement and correlation of solubility of ethosuximide in supercritical carbon dioxide, The Journal of Chemical Thermodynamics, 2019, 131: 104–110

DOI: 10.1016/j.jct.2018.10.032

[11] Jiao Z*, Zha X, Wang Z, Wang X, Fan W, Response surface modeling of drug-loaded micelles preparation by supercritical carbon dioxide evaporation method using Box-Behnken experimental design, Journal of Nanoscience and Nanotechnology, 2019, 19(6): 3616-3620, DOI: 10.1166/jnn.2018.16124

[12] Jiao Z*, Wang X, Han S, Zha X, Xia J, Preparation of vitamin C liposomes by rapid expansion of supercritical solution process: Experiments and optimization, Journal of Drug Delivery Science and Technology, 2019, 51, 1-6

DOI: 10.1016/j.jddst.2019.02.015

[13] Wang W, Han S, Zha X, Cheng J, Song J, Jiao Z*, Response Surface Optimization of Supercritical Carbon Dioxide Extraction of Tea Polyphenols from Green Tea Scraps, Journal of AOAC International，2019, 102(2), 451-456

DOI: 10.5740/jaoacint.18-0163

[14] Jiao Z*, Wang X, Yin Y, Xia J, Preparation and evaluation of vitamin C and folic acid co-loaded antioxidant liposomes, Particulate Science and Technology, 2019, 37(4), 449-455

DOI: 10.1080/02726351.2017.1391907

[15] Wang W, Han S, Jiao Z*, Cheng J, Song J, Antioxidant activity and total polyphenols content of camellia oil extracted by optimized supercritical carbon dioxide, Journal of the American Oil Chemists' Society, 2019, 96(11): 1275–1289

DOI: 10.1002/AOCS.12285

[16] Jiao Z*, Cheng J, Guo M, Han S, Measurement and Correlation of Paeonol Solubility in Supercritical Carbon Dioxide, Journal of Chemical & Engineering Data, 2019, 64(10): 4424−4429

DOI: 10.1021/acs.jced.9b00483

[17] Jiao Z*, Han S, Wang W, Song J, Cheng J, Preparation and optimization of Vitamin E acetate liposomes using a modified RESS process combined with response surface methodology, Particulate Science and Technology,2020, 38(7): 863-875

[20] Yang L, Han Y, Jiao Z*, Measurement and Correlation of Liquid−Liquid Equilibria of Water (1) + 1‑Methylimidazole (2) + [Bmim][PF6] (3) Ternary Systems

between 303.15 and 323.15 K, Journal of Chemical & Engineering Data, 2021, 66, 2134−2142

DOI: 10.1021/acs.jced.1c00041

[21] Han Y, Cheng J, Ruan N, Jiao Z*, Preparation of liposomes composed of supercritical carbon dioxide-philic phospholipids using the rapid expansion of supercritical solution process, Journal of Drug Delivery Science and Technology, 2021, 64, 102568

DOI: 10.1016/j.jddst.2021.102568

[22] Jiao Z*, Ruan N, Wang W, Guo M, Han S, Cheng J, Supercritical carbon dioxide co-extraction of perilla seeds and perilla leaves: experiments and optimization, Separation Science and Technology, 2021, 56(3): 617-630

DOI: 10.1080/01496395.2020.1728320

[23] Ruan N, Jiao Z*,Tang L, Response surface methodology to optimize supercritical carbon dioxide extraction of Polygonum Cuspidatum, Journal of AOAC international，2022, 105(1): 272–281

DOI: 10.1093/jaoacint/qsab108

[24] Wang J, Zhang Y, Sun J*, Jiao Z*, Controllable fabrication of multi-modal porous PLGA scaffolds with different sizes of SPIONs using supercritical CO2 foaming, Journal of Applied Polymer Science, 2022, 139: e52287

DOI: 10.1002/app.52287

[25] Xu Q, Gao P, Wang Y, Jiang W, Wang Z, Jiang Y*, Jiao Z*, Using supercritical carbon dioxide to synthesize polymer nanospheres with an open hole on the surface and the application of spatially structured PS/P(DVB-co-MAA)@Fe3O4/TA@Ag nanocomposites, The Journal of Supercritical Fluids, 2022, 184, 105561.  DIO:10.1016/j.supflu.2022.105561

[26] Zhang Y, Wang J, Zhou J, Sun J*, Jiao Z*, Multi-modal cell structure formation of poly (lactic-co-glycolic acid) /superparamagnetic iron oxide nanoparticles composite scaffolds by supercritical CO2 varying-temperature foaming, Polymers for Advanced Technologies, 2022, 33:1906–1915.

DOI: 10.1002/PAT.5650

[27] Jiao Z*, Zhang M, Yang L, Wang Y, Fu J, Liquid−Liquid Equilibrium for the Ternary System Water + 1‑Methylimidazole + Ionic Liquid ([Hmim][PF6], [Omim][PF6], or [Omim][BF4]) at 303.15K, Journal of Chemical & Engineering Data, 2022, 67, 6, 1474–1480

DOI: 10.1021/acs.jced.2c00150

[28] Zhong Q, Jiao Z*, Nie W, Li Y, Gu N*, Numerical investigation of mass transfer behavior of a gas–liquid two‐phase Taylor flow in a microchannel by a volume‐of‐fluid multiphase flow system, International Journal of Mechanical System Dynamics, 2022, 2, 253–264

DOI: 10.1002/msd2.12049

[29] Wang J, Guo Y, Jiao Z*, Tan J. Zhang M, Zhang Q*, Gu N*, Generation of micro-nano bubbles by magneto induced internal heat for protecting cells from intermittent hypoxic damage, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022, 655, 130289

DOI: 10.1016/j.colsurfa.2022.130289

[30] Qianqian Wang, Shuo Zhang, Zhuang Deng, Yi Zhang, Zhen Jiao*, Preparation of curcumol-loaded magnetic metal- organic framework using supercritical solution impregnation process, Microporous and Mesoporous Materials, 2023, 357, 112612

DOI: 10.1016/j.micromeso.2023.112612

[31] Zhen Jiao*, Zhuang Deng, Yi Zhang, Jinjing Wang, Fabrication Magnetic Composite Scaffolds with Multi-Modal Cell Structure for Enhanced Properties Using Supercritical CO2 Two-step Depressurization Foaming Process, Polymer Bulletin,

DOI: 10.1007/s00289-023-04980-6

近年来授权的专利：

1、焦真，王晨晨，杨前前，王献伟；脂环族环氧聚氨酯丙烯酸酯紫外光固化涂料及其制备方法；ZL 201410212211.1

2、焦真，樊文景，王秀东，王梓屹；天然物中脂性药物的超临界萃取/胶束化一体装置；ZL 201510186337.0

3、焦真，王秀东，王梓屹，查闲君，王晨，殷玉婷；一种从天然物中提取营养素并制剂的系统，ZL 201610072488.8

4、焦真，樊文景，王梓屹，王秀东；一种两亲嵌段聚合物及其制备方法；ZL 201510121569.8

5、焦真，宋俊颖，程江瑞，韩赛，王卫芳，查贤君, 一种具有亲超临界二氧化碳性能的合成磷脂及其制备方法, ZL 201810337209.5

6、焦真，王卫芳，程江瑞，宋俊颖，韩赛，一种改进的超临界抗溶剂法制备聚合物载药颗粒装置，201810554543.6

7、焦真，阚道琴，李乃旭，马全红，周建成，一种基于Radziszewski反应法制备的简单咪唑类化合物的分离工艺，201910348491.1

8、焦真、王甲妲、顾宁、孙剑飞、陈怡，一种微纳气泡的制备方法，ZL 202010912586.4

9、焦真，张溢，孙剑飞，周建成，一种利用超临界流体发泡技术制备骨组织工程支架的方法，ZL202010155938.6

10、焦真; 王倩倩; 李乃旭; 顾宁，一种基于超临界浸渍制备磁性MOF载药系统的方法，ZL202210458332.9