赵春杰教授的研究团队主要围绕学习记忆、情感等脑高级功能开展研究，针对神经发育相关疾病如智力障碍、自闭症、FOXG1综合征、癫痫等疾病的致病基因，通过基因编辑建立人类疾病的动物模型。特别聚焦于大脑皮层等行使脑高级功能的重要脑区，揭示神经干细胞的增殖、分化、神经元迁移和成熟的调控机制，探讨神经环路兴奋性与抑制性平衡维持机制，旨在揭示相关疾病的发生机制，为诊断和干预提供新的思路。

1    国家杰出青年科学基金获得者

2    “新世纪百千万人才工程”国家级人选

3    国务院政府特殊津贴专家

4    江苏省“333高层次人才培养工程”中青年科技领军人才

5    江苏省有突出贡献中青年专家

6    江苏省“333”工程突出贡献奖

7    江苏省特聘教授

8    全国“五·一”巾帼标兵

9    江苏省十行百星“科技之星”

赵春杰教授承担着国家重点研发计划、国家自然科学基金重点项目等科研任务，曾作为首席科学家主持国家973和863项目，在智力障碍、自闭症、FOXG1综合征、癫痫等疾病研究领域取得系列研究成果，成果发表于Cell、Development、J. Neurosci.、Cerebral Cortex等神经科学领域国际著名学术刊物，引起领域内同行广泛关注。

代表性成果：

1.Han X^#, Wei Y^#, WuX, Gao J, Yang Z, Zhao C^*.PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors byControlling Asymmetric Cell Division. Cereb Cortex. 2020,Jan 10; 30 (1):406-420, doi: 10.1093/cercor/bhz146.

2.Du A^#, Wu X^#, ChenH, Bai QR, Han X, Liu B, Zhang X, Ding Z, Shen Q, Zhao C*. Foxg1 DirectlyRepresses Dbx1 to Maintain the POAand Subsequently Regulates the Ventral Telencephalic Patterning. Cereb Cortex. 2019, Dec17; 29 (12): 4968-4981.doi: 10.1093/cercor/bhz037.

3.Chen D, Wang C, Li M, Yuan Y, Chen H*,Zhang W*, Zhao C*. Loss of Foxg1 Impairs the Development ofCortical SST-interneurons Leading to Abnormal Emotional and Social Behaviors. Cereb Cortex. 2019Aug 29 (8), 3666-3682, doi: 10.1093/cercor/bhz114.

4.Shen W^#, Ba R^#, SuY, Ni Y, Chen D, Xie W, Pleasure SJ, ZhaoC*. Foxg1 regulates the postnatal development of cortical interneurons. Cereb Cortex. 2019 Apr.29 (4), 1547–1560, doi: 10.1093/cercor/bhy051.

5.Xu M^#, Han X^#,Liu R, Qi C, Yang Z, Zhao C*, Gao J*. PDK1 DeficitImpairs the Development of the Dentate Gyrus in Mice.Cereb Cortex.2019 Mar 29 (3) 1185-1198. doi: 10.1093/cercor/bhy024.

6.Yang Y^#, Shen W^#, Ni Y, Su Y, YangZ, ZhaoC*. Impaired interneuron development after Foxg1disruption. Cerebral Cortex.doi:10.1093/cercor/bhv297. 2017，Jan 27（1）793-808.

7.Wu X, Gu X, Han X, Du A, Jiang Y, ZhangX, Wang Y, Cao G, ZhaoC*. A Novel Function for FoxM1 in Interkinetic Nuclear Migration in the DevelopingTelencephalon And Anxiety-related Behavior.The Journal of Neuroscience.  2014Jan; 34(4):1510-1522.

8.Tian C, Gong Y, Yang Y, Shen W, Wang K,Liu J, Xu B, Zhao J, Zhao C*. Foxg1 Has An essential Role in Postnatal Development of The Dentategyrus. The Journal of Neuroscience.2012. Feb., 32(9):2931-2949.

9.Zhao C*, Avilés C, AbelRA, Almli CR, McQuillen P, Pleasure SJ*. Hippocampal and Visuospatial Learning Defectsin Mice with Deletion of Frizzled9, a Gene in the Williams Syndrome DeletionInterval.Development.2005 Jun; 132(12):2917-2927.

10.Zhao C,Takita J, Tanaka Y, Setou M, Nakagawa T, Takeda S, Yang HW, Terada S, Nakata T,Takei Y, Saito M, Tsuji S, Hayashi Y, Hirokawa N*. Charcot-Marie-Tooth DiseaseType 2A Caused byMutation in a Microtubule Motor KIF1B. Cell. 2001 Jun 1;105(5):587-597.（cover story）