I have long standing interests in nanomedicine, and now my research focus on the application of nanomedical materials in the diagnosis and treatment of tumors. My group will study the design and construction of targeted nanomaterials, tumor imaging and the influence of materials on tumor prognosis, explore the roles of immune response and autophagy in tumor therapy and their regulation, and find the key pathway signal molecules of anti-tumor effects of these nanomaterials. The results of our study contribute to the development of new cancer diagnostic and therapeutic agents.

Teaching First Prize of Southeast University

Excellent Communist Party Member of Southeast University

Selected Publications

1.Peidang Liu,Huimin Shao, Yan Kong, Dayong Wang. Effect of graphene oxide exposure onintestinal Wnt signaling in nematode Caenorhabditis elegans. J EnvironSCI-CHINA, 2020, 88: 200-208.

2.Jing Zhao, Peidang Liu*, Jun Ma, Dongdong Li,Huiquan Yang, Wenbin Chen, Yaowen Jiang. Enhancement of radiosensitization bysilver nanoparticles functionalized with polyethylene glycol and aptamer As1411for glioma irradiation therapy. Int J Nanomed, 2019, 14: 9483-9496.

3.Peidang Liu, Dan Li, Wenjie Li, Dayong Wang. Mitochondrial unfolded protein response to microgravitystress in nematode Caenorhabditis elegans. Sci Rep, 2019, 9(1): 16474

4.Peidang Liu*,Huiquan Yang, Wenbin Chen, Jing Zhao, Dongdong Li. Silver nanotrianglesand chemotherapy drugs synergistically induce apoptosis in breast cancer cellsvia production of reactive oxygen species. J Nanopart Res, 2019, 21(11):250.

5.Peidang Liu,Huimin Shao, Xuecheng Ding, Ruilong Yang, Qi Rui, Dayong Wang. Dysregulation ofneuronal Gαo signaling by graphene oxide in nematode caenorhabditis elegans.Sci Rep, 2019, 9(1): 6026

6. Feng Chen, Xiao Hong Zhang, Xiao Dan Hu, Pei Dang Liu* and Hai Qian Zhang*. The effects of combined selenium nanoparticles and radiation therapy on breast cancer cells in vitro. Artif Cells Nanomed Biotechnol. 2018, 46(5): 937-948.

7. Feng Chen, Xiao Hong Zhang, Xiao Dan Hu, Pei Dang Liu* and Hai Qian Zhang*. Mechanisms of increased in vitro radio sensitivity by a ceria nanoparticle-neogambogic acid combination. Nanosci and Nanotech Lett. 2018, 10(2): 259-266

8. Ningning Ma, Peidang Liu, Nongyue He, Ning Gu, Fu-Gen Wu, and Zhan Chen. Action of Gold Nanospikes-Based Nanoradiosensitizers: Cellular Internalization, Radiotherapy, and Autophagy. ACS Appl Mater Interfaces, 2017, 9(37): 31526-31542.

9. Peidang Liu*, Haizhen Jin, Zhirui Guo, Jun Ma, Jing Zhao, Dongdong Li, Hao Wu and Ning Gu*. Silver nanoparticles outperform gold nanoparticles in radiosensitizing U251 cells in vitro and in an intracranial mouse model of glioma. Int J Nanomed. 2016; 11: 5003-5014.

10. Feng Chen, Xiaohong Zhang, Xiaodan Hu, Weizhang, Rong Zeng, Peidang Liu* and Haiqian Zhang*. Synthesis and characteristics of nanorods of gadolinium hydroxide and gadolinium oxide. J Alloy Compd. 2016, 664: 311-316.

11. Hao Wu, Jun Lin, Peidang Liu, Zhihai Huang, Peng Zhao, Haizhen Jin, Jun Ma, Longping Wen, Ning Gu. Reactive oxygen species acts as executor in radiation enhancement and autophagy inducing by AgNPs. Biomaterials. 2016; 101: 1-9.

12. Zhichao Lou, Zhiwei Zhou, Wei Zhang, Xiaohong Zhang, Xiaodan Hu, Peidang Liu*, Haiqian Zhang*. Magnetized bentonite by Fe3O4 nanoparticles treated as adsorbent formethylene blue removal from aqueous solution: Synthesis, characterization, mechanism, kinetics and regeneration. J Taiwan Inst Chem E. 2015, 49:199-205.

13. Feng Chen, Xiaohong Zhang, Xiaodan Hu, Wei Zhang, Zhichao Lou, Lihua Xie, Peidang Liu* and Haiqian Zhang*. Enhancement of radiotherapy by ceria nanoparticles modified with neogambogic acid in breast cancer cells. Int J Nanomed. 2015, 10:4957-4969.

14. Xiangyu Su, Peidang Liu, Hao Wu, Ning Gu. Enhancement of radiosensitization by metal-based nanoparticles in cancer radiation therapy. Cancer Biol Med, 2014, 11 (2): 86-91.

15. Xiaodong Zhang, Fugen Wu, Peidang Liu, Ning Gu, Zhan Chen. Enhanced fluorescence of gold nanoclusters composed of HAuCl4 and histidine by glutathione: glutathione detection and selective cancer cell imaging. Small, 2014, 10 (24): 5170-5177.

16. Peidang Liu, Zhihai Huang, Zhongwen Chen, Ruizhi Xu, Hao Wu, Fengchao Zang, Cailian Wang, and Ning Gu. Silver nanoparticles: a novel radiation sensitizer for glioma? Nanoscale, 2013, 5 (23): 11829-11836.

17. Peidang Liu, Zhihai Huang, Ning Gu. Exposure to silver nanoparticles does not affect cognitive outcome or hippocampal neurogenesis in adult mice. Ecotox Environ Safe, 2013, 87: 124-130.

18.刘培党, 史婷婷, 朱建宝, 曾水林, 顾宁. 纳米银联合放疗对大鼠胶质瘤内iNOS表达和NO水平的影响. 神经解剖学杂志, 2013, 29 (3): 275-279.

19. Peidang Liu, Kewen He, Yinxia Li, Qiuli Wu, Peng Yang, and Dayong Wang. Exposure to mercury causes formation of male-specific structural deficits by inducing oxidative damage in nematodes. Ecotox Environ Safe, 2012, 79: 90-100.

20. Qiuli Wu#, Peidang Liu#, Yinxia Li, Min Du, Xiaojuan Xing, and Dayong Wang. Inhibition of ROS elevation and damage on mitochondrial function prevents lead-induced neurotoxic effects on structures and functions of AFD neurons in Caenorhabditis elegans. J Environ SCI-CHINA, 2012, 24 (4): 733-742.

21. Peidang Liu, Ling Chen, Xiuying Bai, Andrew Karaplis, Dengshun Miao, and Ning Gu. Impairment of spatial learning and memory in transgenic mice overexpressing human fibroblast growth factor-23. Brain Res, 2011, 1412: 9-17.