主持国家科学自然基金及江苏省科学自然基金等课题:
1 国家科学自然基金青年基金 (NO.81400300)。23万,2014.1-2017.12,负责人。
2 江苏省青年科学自然基金(NO.BK20130642)。20万, 2014.6-2017.6,负责人。
参与其他国家科学自然基金项目多项:
1 国家科学自然基金面上项目(NO.81773796)。
2 国家科学自然基金青年项目(NO.81600045)。
3 国家科学自然基金青年项目(NO.81803182)。
论文:
1. Dai X, Cheng Y, Wang C, Huang J, Chao J*. Role of Circular RNAs in Visceral Organ Fibrosis. Food Chem Toxicol. 2021.150:112074.
2. ChengY#, Luo W, Li Z, Cao M, Zhu Z, Han C, Dai X, Zhang W, Wang J, Yao H, ChaoJ*. CircRNA-012091/PPP1R13Bmediated lung fibrotic response in silicosis via ERstress and autophagy. Am J Resp Cell Mol Biol.2019, 61(3):380-391.
3. ChengYS#, Chao J, Chen C, Lv LL, Han YC, Liu BC*. The PKCβ-p66shc-NADPH oxidasepathway plays a crucial role in diabetic nephropathy. J Pharm Pharmacol. 2019Mar;71(3):338-347.
4. Fang S#, Guo H#, Cheng Y#, Zhou Z, Zhang W, Han B, Luo W, Wang J, Xie W*, ChaoJ*.circHECTD1 promotes the silica-induced pulmonary endothelial-mesenchymaltransition via HECTD1. Cell Death Dis. 2018 Mar;9(3):396.
5. Liu H, Cheng Y, Yang J, Wang W, Fang S, Zhang W, Han B, Zhou Z, Yao H, Chao J*, Liao H*: BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silicosis. Cell Death Dis. 2017; 8:e2657.
8. Liu H, Dai X, Cheng Y, Fang S,Zhang Y, Wang X, Zhang W, Liao H, Yao H, Chao J#: MCPIP1 mediates silica -induced cell migration in human pulmonary fibroblasts. Am J Physiol-Lung C. 2016; 310(2):L121-L132.
9.Chu H, Wang W, Luo W, Zhang W, Cheng Y, Huang J, Wang J, Dai X, Fang S, Chao J. CircHECTD1 mediates pulmonary fibroblast activation via HECTD1. Ther Adv Chronic Dis. 2019 Nov 27;10:2040622319891558.
10.Chen L, Luo W, Zhang W, Chu H, Wang J, Dai X, Cheng Y, Zhu T, Chao J. circDLPAG4/HECTD1 mediates ischaemia/reperfusion injury in endothelial cells via ER stress. RNA Biol. 2020 Feb;17(2):240-253.
11.Jiang R, Liao Y, Yang F, Cheng Y, Dai X, Chao J. SPIO nanoparticle-labeled bone marrow mesenchymal stem cells inhibit pulmonary EndoMT induced by SiO2. Exp Cell Res. 2019 Oct 1;383(1):111492.
12.Cao Z, Xiao Q, Dai X, Zhou Z, Jiang R, Cheng Y, Yang X, Guo H, Wang J, Xi Z, Yao H, Chao J. circHIPK2-mediated σ-1R promotes endoplasmic reticulum stress in human pulmonary fibroblasts exposed to silica. Cell Death Dis. 2017 Dec 13;8(12):3212.